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  4. XO-chromosomal abnormality in human beings causes

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Q. XO-chromosomal abnormality in human beings causes

AIPMTAIPMT 1992Principles of Inheritance and Variation

Solution:

Turner’s syndrome is characterised by the monosomy of XO type. These are immature sterile females with webbed neck. Klinefelter’s syndrome is characterised by trisomy (XXY). These are male individuals, who are phenotypically fairly normal but have a fairly low sperm count and therefore sterile. Down’s syndrome is caused due to the presence of extra chromosome 21 (trisomy 21).