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  4. Which of the following statement is true for the packaging of DNA in eukaryotes? A.DNA is packaged with a set of basic protein called histone. B. Histone contain negatively charged amino acid in its side chain. C. DNA packed with histone octamer are called nucleosome. D. Nuclesome is further packed to form chromatin fibre.

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Q. Which of the following statement is true for the packaging of DNA in eukaryotes?
A.DNA is packaged with a set of basic protein called histone.
B. Histone contain negatively charged amino acid in its side chain.
C. DNA packed with histone octamer are called nucleosome.
D. Nuclesome is further packed to form chromatin fibre.

NTA AbhyasNTA Abhyas 2020Molecular Basis of Inheritance

Solution:

In eukaryotes, DNA organisation is much more complex. There is a set of positively charged, basic proteins called histones. A protein acquires charge depending upon the abundance of amino acids residues with charged side chains. Histones are rich in the basic amino acid residues lysine and arginine. Both the amino acid residues carry positive charges in their side chains. Histones are organised to form a unit of eight molecules called histone octamer. The negatively charged DNA is wrapped around the positively charged histone octamer to form a structure called nucleosome.