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Q. Which of the following is most appropriate regarding kidney function regulation? Stimulation of

AMUAMU 2015Excretory Products and their Elimination

Solution:

Renin Angiotensin mechanism increases the Glomerular Filtration Rate (GFR), while atrial natriuretic factor decreases GFR. A reduced blood pressure causes reduced GFR, result in release of renin by juxta glomerular cells. Renin converts angiotensinogen into angiotensin-II and angiotensin-II. The latter increases the BP by constriction of arterioles and thus increase GFR. ANF is produced by atria of heart and results in decrease blood pressure by reducing $H_{2}O$ , Na and adipose loads on circulatory system.