Question

Which of the following is incorrect about nucleosome?

• A. Histones are organized to form a unit of eight molecules called a histone octamer
• B. The negatively charged DNA is wrapped around the positively charged histone octamer.
• C. Nucleosomes constitute the repeating unit of a structure in nucleus called chromatin
• D. The nucleosomes in chromatin are seen as 'Beads on string' structure when viewed under light microscope.

Answer 1

Answer: (D)

The nucleosome chain represents 'beads on string'-like structure (representing chromatin) when viewed under electron microscope. This chromatin undergoes further coiling to form chromatin fibres. These chromatin fibres undergo further coiling to form chromosomes, which are distinctly visible during metaphase of cell division.