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Q.
Which of the following conditions will shift the oxygen dissociation curve to the right?
NTA AbhyasNTA Abhyas 2020Breathing and Exchange of Gases
Solution:
Oxygen binds with hemoglobin in a reversible manner to form oxyhemoglobin. A maximum of four oxygen molecules is carried by each Hb. The binding of oxygen is related to the partial pressure of $O_{2}$ whereas partial pressure of $C O_{2}$ , hydrogen ion concentration, and temperature are factors interfering with its binding. The factors which are favorable for formation of oxyhemoglobin in the alveoli are high $p O_{2}$ , lesser $H^{+}$ concentration, low $p C O_{2,}$ and lower temperature. These conditions shift the oxygen dissociation curve to the left. The low $p O_{2}$ , high $p C O_{2}$ , high $H^{+}$ concentration, and higher temperature in the tissues are all the conditions leading to dissociation of oxygen from the oxyhemoglobin. These conditions shift the oxygen dissociation curve to the right.