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Q. Which of the amines can not be prepared by Gabriel's phthalimide synthesis?

NTA AbhyasNTA Abhyas 2022

Solution:

The Gabriel synthesis is a chemical reaction that transforms primary alkyl halides into primary amines. Traditionally, the reaction uses potassium phthalimide. Gabriel's phthalimide synthesis involves $S_{N}2$ reaction, thus $3^{o}$ butyl amine cannot be prepared through this method.