Question

What is the increasing order of reactivity of the following towards base catalysed hydrolysis reaction?
(I) $CH_3CONH_2$
(II) $CH_3COOCH_3$
(III) $CH_3COOCOCH_3$
(IV) $C_6H_5COCl$

• A. $I < III < II < IV$
• B. $IV < III < II < I$
• C. $I < II < III < IV $
• D. $I < IV < II < III$

Answer 1

Answer: (C)

Rate of hydrolysis follow the order of reactivity of acid derivatives towards nucleophilic acyl substitution