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  4. What is the advantage in clinical use of humulin (human insulin: produced through rDNA technique) over use of conventional ox or pig insulin?

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Q. What is the advantage in clinical use of humulin (human insulin: produced through rDNA technique) over use of conventional ox or pig insulin?

COMEDKCOMEDK 2015Biotechnology and its Applications

Solution:

Earlier, insulin for curing diabetes was used to be extracted from pancreas of slaughtered pigs and cattle. This conventional insulin was slightly different from human insulin and its over use resulted in some undesirable side effects, e.g. certain immunological problems such as allergy. However, humulin produced through rDNA technique is similar to that of human insulin and does not cause any immunological problems. It is thus advantageous over conventional type of insulin.