Question

What is Bohr's effect?

• A. A rise in levels of $p CO _{2}$ or fall in $pH$ decreases the oxygen affinity of haemoglobin
• B. Decrease in levels of $p CO _{2}$ or fall in $pH$ decreases the oxygen affinity of haemoglobin
• C. A rise in levels of $p CO _{2}$ or increase in $pH$ decreases the oxygen affinity of haemoglobin
• D. Shifting of the oxygen-haemoglobin curve to left

Answer 1

Answer: (A)

Bohr's effect is described as a rise in $p CO _{2}$ (or fall in $pH$ ) which decreases the oxygen affinity of haemoglobin thus, raising the $P _{50}$ value and shifts the curve to the right. Conversely, a fall in $p CO _{2}$ and rise in the $pH$ increases oxygen affinity of haemoglobin $\left( P _{50}\right.$ value is the value of $p O _{2}$ at which haemoglobin is $50 \%$ saturated with oxygen to form haemoglobin).