1. Tardigrade
  2. Question
  3. Biology
  4. What gets removed during the processing of proinsulin to insulin?

Question Error Report

Thank you for reporting, we will resolve it shortly

Back to Question

Q. What gets removed during the processing of "proinsulin" to "insulin"?

NTA AbhyasNTA Abhyas 2022

Solution:

In mammals, including humans, insulin is synthesised as a pro-hormone (like a pro-enzyme, the pro-hormone also needs to be processed before it becomes a fully mature and functional hormone) which contains an extra stretch called the C peptide. This C peptide is not present in the mature insulin and is removed during maturation into active insulin.