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  4. Toxic agents present in food which interfere with thyroxine synthesis lead to the development of

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Q. Toxic agents present in food which interfere with thyroxine synthesis lead to the development of

AIPMTAIPMT 2010Chemical Coordination and Integration

Solution:

Simple goitre is caused by deficiency of iodine in diet because iodine is needed for the synthesis of thyroid hormone. Toxic agents present in the food may also interfere with thyroxine (thyroid hormones) synthesis. It causes thyroid enlargement. It may lead to cretinism or myxoedema. This disease is common in hilly areas.