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Q. The total number of different combinations of one or more letters which can be made from the letters of the word "MISSISSIPPI" is

Permutations and Combinations

Solution:

Here we have $1 M, 4I, 4S$ and $2P.$
Therefore total number of selections of one or more letters
$= (1 + 1) (4 + 1) (4 + 1)(2 + 1) - 1 = 149$