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  4. The prokaryote that is credited with construction of the first recombinant DNA by linking an antibiotic resistance gene with its native plasmid is

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Q. The prokaryote that is credited with construction of the first recombinant DNA by linking an antibiotic resistance gene with its native plasmid is

NTA AbhyasNTA Abhyas 2022

Solution:

The construction of the first recombinant DNA by linking a gene encoding antibiotic resistance with a native plasmid of Salmonella typhimurium was accomplished in 1972 by Stanley Cohen and Herbert Boyer. This rDNA was transferred in Escherichia coli which could replicate and produce multiple copies.