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  3. Chemistry
  4. The pKa of acetyl salicylic acid (aspirin) is 3.5. The pH of gastric juice in human stomach is about 2-3 and the pH in the small intestine is about 8. Aspirin will be

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Q. The $ pK_a$ of acetyl salicylic acid (aspirin) is $3.5$. The pH of gastric juice in human stomach is about $2-3$ and the pH in the small intestine is about $8$. Aspirin will be

IIT JEEIIT JEE 1988Equilibrium

Solution:

In stomach, pH is $2-3$, i.e. strongly acidic and aspirin will be almost unionised here due to common ion effect. However. pH in small intestine is $8$, basic, aspirin will be neutralised here.