Given, $\log _{2}(x-1)=2 \log _{2}(x-3)$
$\Rightarrow \log _{2}(x-1)=\log _{2}(x-3)^{2}$
$\Rightarrow x-1=(x-3)^{2}$
$\Rightarrow x-1=x^{2}+9-6 x$
$\Rightarrow x^{2}-7 x+10=0$
$\Rightarrow (x-2)(x-5)=0$
$\Rightarrow x=2,5$
Since, $x=2$ does not satisfis the equation.
So, $x=5$ is the only solution.
Hence, number of solution is one.