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Q. The most important chemical method to resolve a racemic mixture makes use of the formation of

AIPMTAIPMT 1994Organic Chemistry – Some Basic Principles and Techniques

Solution:

Diastereomers have different physical properties such as melting point, boiling point, solubilities in a given solvent, densities, refractive index, etc. Because of the differences in the boiling points and the solubilities, they can be separated by fractional distillation and fractional crystallisation.