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Q. The increasing order of $pK_{a}$ of the following amino acids in aqueous solution is Gly, Asp, Lys, Arg

NTA AbhyasNTA Abhyas 2020Biomolecules

Solution:

Order of acidic strength

Solution

Solution

$K_{a} \propto $ number of —COOH groups

$ \propto \frac{1}{n o . o f — N H_{2} g r o u p s}$

So, $pK_{a} \propto \frac{1}{K_{a}}$
$Asp < Gly < Lys < Arg$