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  4. The cri-du-chat syndrome is caused by change in chromosome structure involving

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Q. The "cri-du-chat" syndrome is caused by change in chromosome structure involving

AIIMSAIIMS 2005Principles of Inheritance and Variation

Solution:

Cri-du-Chat syndrome (Cat-cry syndrome) was discovered by Lejeune in 1963 and is due to the deletion of a large part of the small arm of one of the 5th autosomes.