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Q. The correct sequence of the first six amino acids in HbA beta globulin peptide is

NTA AbhyasNTA Abhyas 2020Principles of Inheritance and Variation

Solution:

HbA is adult hemoglobin. The first six peptides on its beta-globin chain are Valine - Histidine - Leucine - Threonine - Proline - Glutamic acid. In sickle cell anemia, HbS is formed. It has valine instead of glutamic acid in the 6th position.