The given series is in GP. Hence, its sum
$S=\frac{1\left\{(1+x)^{20+1}-1\right\}}{(1+x)-1}=\frac{(1+x)^{21}-1}{x}$
Therefore, the required coefficient of $x^{10}$ in the expansion of $\frac{(1+x)^{21}-1}{x}$
$=$ Coefficient of $x^{11}$ in the expansion of $(1+x)^{21}-1$
$={ }^{21} C_{11}$