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  4. Telomerase is an enzyme which is a

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Q. Telomerase is an enzyme which is a

AIPMTAIPMT 2005Molecular Basis of Inheritance

Solution:

Telomerase is a ribonucleoprotein molecule that is enzymatic in nature. It uses a special mechanism for the synthesis of DNA at telomeric ends. The DNA repeat sequence of telomere has one G-rich strand and other C rich strand. The G-rich strand has a single stranded overhand. This overhand works as a primer and for its elongation uses as template the RNA component of telomerase enzyme. Thus telomerase synthesizes only the G-rich strand of telomeres.