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  4. Study the following statements regarding the chemiosmotic hypothesis in mitochondria and select the CORRECT ones (i) F1 headpiece contains the site for the synthesis of ATP from ADP + Pi . (ii) F0 part forms the channel through which protons crosses the inner membrane. (iii) For each ATP produced, 2H+ pass through F0 from the intermembrane space to the matrix down the electrochemical proton gradient.

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Q. Study the following statements regarding the chemiosmotic hypothesis in mitochondria and select the CORRECT ones
(i) $F_{1}$ headpiece contains the site for the synthesis of ATP from $ADP \, + \, Pi$ .
(ii) $F_{0}$ part forms the channel through which protons crosses the inner membrane.
(iii) For each ATP produced, $2H^{+}$ pass through $F_{0}$ from the intermembrane space to the matrix down the electrochemical proton gradient.

NTA AbhyasNTA Abhyas 2020Photosynthesis in Higher Plants

Solution:

Chemiosmotic hypothesis was proposed by Peter Mitchell. According to the hypothesis which occurs in the mitochondria, ATP formation is a result of proton motive force that is generated due to the redox reactions taking place in the electron transport chain. Protons are pumped in the intermembrane space as electrons are passed through the electron transport chain in the cristae of mitochondria. Proton gradient is created across the matrix and intermembrane space. Protons are pumped through the $F_{1}-F_{0}$ complex resulting in formation of ATP from ADP and inorganic phosphate.