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Q. Sickle-cell anaemia is due to the following mutant gene :

KCETKCET 2018Principles of Inheritance and Variation

Solution:

Sickle cell anaemia is a form of point mutation, where a single nitrogen base (CAC) of the codon for glutamic acid is changed to (GUG) for valine So, the correct answer is 'CAC - GUG'