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  4. Sickle-cell anaemia is an autosome linked recessive trait that can be transmitted from parents to the offspring when both the partners are carrier for all the gene (or heterozygous). The disease is controlled by a single pair of allele, HbA Hbs Out of the three possible genotypes only homozygous individuals for HbS (Hbs Hbs) are lethal. Identify X, Y Z <img class=img-fluid question-image alt=image src=https://cdn.tardigrade.in/img/question/biology/78a98d189e8acc86d7284f10c06bc29e-.png /> <img class=img-fluid question-image alt=image src=https://cdn.tardigrade.in/img/question/biology/e58f365449bc4be1aaaa90dbe29db941-.png />

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Q. Sickle-cell anaemia is an autosome linked recessive trait that can be transmitted from parents to the offspring when both the partners are carrier for all the gene (or heterozygous). The disease is controlled by a single pair of allele, $Hb^{A}$ & $Hb^{s}$ Out of the three possible genotypes only homozygous individuals for $HbS (Hb^{s} Hb^{s})$ are lethal. Identify $X, Y$ & $Z$
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Principles of Inheritance and Variation

Solution:

Correct answer is (a) X - CAC; Y - GTG; Z - Val