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Q. Select the correct statements about $ lac $ operon.
(1) Glucose or galactose may bind with the represser and inactivate it
(2) In the absence of lactose, the represser binds with the operator region
(3) The Z-gene codes for permease
(4) This was elucidated by Francois Jacob and Jacques Monod

BHUBHU 2010

Solution:

In prokaryotes, a hypothesis was given in $1961$ to explain the protein synthesis regulation. This hypothesis was given by F Jacob and J Monod and for this awarded Nobel Prize in $1965$, the hypothesis was known by the name of Operon model. The operator gene is the segment of DNA, which exercise a control over transcriptions. In the absence of lactose the represser binds with the operator gene.