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  4. RNA polymerase contains multiple polypeptide units. For initiating RNA synthesis it requires

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Q. RNA polymerase contains multiple polypeptide units. For initiating RNA synthesis it requires

JIPMERJIPMER 2013Molecular Basis of Inheritance

Solution:

RNA polymerase consists of a core enzyme, with subunits $ (\alpha ,\alpha ,\beta ,\beta ,\omega)$ and a sigma $ (\sigma ) $ factor. The sigma factor initiates transcription of mRNA on the DNA template and directs the binding of the enzyme to the promoter region. The core enzyme continues transcription.