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  4. Removal of RNA pol III from the nucleoplasm will affect the synthesis of .

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Q. Removal of RNA pol III from the nucleoplasm will affect the synthesis of ____.

JIPMERJIPMER 2014Molecular Basis of Inheritance

Solution:

Eukaryotes have three RNA polymerases. RNA polymerase I is located in the nucleolus and transcribes for rRNAs (28S, 18S and 5.8S), RNA polymerase II is localized to the nucleoplasm and used for hnRNA, mRNA synthesis and RNA polymerase III is localised to the nucleus, possibly the nucleolar-nucleoplasm interface and transcribes for tRNA, 5SrRNA and snRNAs. So, removal of RNA polymerase III will affect the synthesis of tRNA.