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  4. Physical association of genes on a chromosome is called

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Q. Physical association of genes on a chromosome is called

KEAMKEAM 2015Principles of Inheritance and Variation

Solution:

Linkage is the phenomenon of certain genes staying together during inheritance through generations without any change or separation due to their presence on the same chromosome. Linkage was first suggested by Sutton and Boveri (1902-1903) when they propounded the famous “chromosomal theory of inheritance.” Bateson and Punnett (1906) while working on sweet pea found that the factors for certain characters do not show independent assortment. However, it was Morgan (1910) who clearly proved and defined linkage on the basis of his breeding experiments in fruitfly Drosophila melanogaster. In 1911, Morgan and Castle proposed chromosome theory of linkage.