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  4. Person with blood group AB is considered as universal recipient because he has

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Q. Person with blood group AB is considered as universal recipient because he has

AIPMTAIPMT 2014Body Fluids and Circulation

Solution:

ABO blood groups are determined by the gene I (isoagglutinin). There are three alleles, IA, IB and 1° of this gene. IA allele is responsible for formation of A antigen, while IB allele is responsible for formation of B antigen. People with blood group A have the A antigen on the surface of their RBCs, and antibodies to antigen B in their plasma. Persons with blood group B have B antigen on their RBCs, and antibodies against A antigen in their plasma. Individuals with AB blood group have both antigen A and B on their RBCs, and no antibodies for either of the antigen in their plasma. Type O individuals are without A and B antigens on their RBCs, but have antibodies for both these antigens in their plasma. Individuals with blood group AB can receive blood of A, B or O group, while those with blood group O can donate blood to anyone.