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  4. Muscle fatigue is due to:

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Q. Muscle fatigue is due to:

ManipalManipal 2005

Solution:

Due to continuous contraction, a muscle exhausts its stored ATP and glycogen molecules and accumulates lactic acid, which gradually retards and finally stops the contraction activity of muscle cell. This situation is known as fatigue of a muscle.
After rest for some time, this fatigued muscle regains its contractivity. During rest time, the lactic acid is reconverted to be utilized in the formation of ATP.