Question

Mark the correct statements about denaturation of proteins.

• A. After denaturation, the biological activity of the protein is destroyed
• B. The primary structure of the protein does not change
• C. Fibrous proteins are converted into globular proteins
• D. Curdling of milk is an example of denaturation of protein

Answer 1

Answer: (A), (B)

When a protein in its nature form, is subjected to physical change in $pH$, the hydrogen bonds are disturbed. Due to this, globules unfold and helix get uncoiled and protein loses its biological acitivity. This is called denaturation of protein. During denaturation $2^{\circ}$ and $3^{\circ}$ structures are destroyed but $1^{\circ}$ structure remain intact.