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Q. Karyotype of Down’s syndrome has how many chromosomes?

Principles of Inheritance and Variation

Solution:

Karyotype of people suffering from Down’s syndrome have $47$ chromosomes ( $45 + XY$ in males, $45 + XX$ in females) instead of $46$. It is caused due to the presence of an extra chromosome, i.e. chromosome number $21$. Thus, it is also known as $21$ trisomy.