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  4. In human females, meiosis-II is not completed until

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Q. In human females, meiosis-II is not completed until

AIPMTAIPMT 2015Human Reproduction

Solution:

In human beings, ovum is released from the ovary in the secondary oocyte stage. The maturation of secondary oocyte is completed in the mother's oviduct (Fallopian tube) usually after the sperm has entered the secondary oocyte for fertilisation. Entry : of the sperm restarts the cell cycle breaking down MPF (M-phase promoting factor) and turning on APC (Anaphase promoting complex). Completion of meiosis II converts the secondary oocyte into a fertilised ovum (egg) or zygote (and also a second polar body).