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  4. In Drosophila the XXY condition leads to femaleness whereas in human beings the same condition leads to Klienfelter's syndrome in male. It proves

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Q. In Drosophila the XXY condition leads to femaleness whereas in human beings the same condition leads to Klienfelter's syndrome in male. It proves

AIPMTAIPMT 2000Principles of Inheritance and Variation

Solution:

In Drosophila, XXY condition leads to femaleness. Cytological examination have suggested that Y-chromosome does not play any role in determination of sex in Drosophila. In human being, XXY is phenotypically male with underdeveloped testes gynecomastia and often mental retardation. It is caused by the union of a non-disjunct XX egg and sperm and a normal X egg and abnormal XY sperm. This indicates that in human being Y chromosome is active in sex determination.