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Q. In assigning RS configuration which among the following groups has highest priority ?

MHT CETMHT CET 2017Organic Chemistry – Some Basic Principles and Techniques

Solution:

In R-S configuration, priority sequence is decided by the atoms directly attached to the chiral carbon arranged in decreasing atomic number.
From the given groups, sulphur (S) has the highest atomic number i.e., 16 therefore, it gets highest priority.