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  4. If the mother is Rh-ve and the father is Rh+ve, the condition of erythroblastosis foetalis may occur. This condition may be avoided by administrating anti-Rh antibodies to

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Q. If the mother is Rh-ve and the father is Rh+ve, the condition of erythroblastosis foetalis may occur. This condition may be avoided by administrating anti-Rh antibodies to

NTA AbhyasNTA Abhyas 2020Body Fluids and Circulation

Solution:

If a Rh-ve pregnant mother is having a Rh+ve foetus, then Rh antigens of the foetus are not exposed to the Rh-ve blood of the mother in the first pregnancy because the two bloods are well separated by the placenta. But during the delivery of the first Rh+ve child, some amount of foetal blood is exposed to the maternal blood. In this condition, the mother starts preparing antibodies against Rh antigens in her blood. These antibodies from the mother (Rh-ve) can leak into the blood of the foetus (Rh+ve) during next Rh+ve pregnancies and destroy the foetal RBCs.