Question

If the acidic, basic and hydrophobic residues of proteins are considered to be red, green and blue in colour, respectively, then a globular protein in aqueous solution would have

• A. red and blue on the surface and green at the core
• B. red and green on the surface and blue at the core
• C. blue on the surface and red and green at the core
• D. blue and green on the surface and red a t the core

Answer 1

Answer: (B)

Globular proteins are folded such that their tertiary structure consists of the polar or hydrophilic amino acids (both acidic and basic) arranged on the outside surface and non-polar or hydrophobic amino acids on the inside or core of the three dimensional shape. Thus, the globular protein mentioned in the question would have red and green colour on the surface and blue colour at the core in aqueous solution.