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  4. If for some reason the parietal cells of the gut epithelium become partially non-functional, what is likely to happen?

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Q. If for some reason the parietal cells of the gut epithelium become partially non-functional, what is likely to happen?

AIPMTAIPMT 2010Digestion and Absorption

Solution:

Parietal or oxyntic cells secrete HCl (due to which pH of stomach is highly acidic) and intrinsic factor. Parietal glands also secrete pepsinogen to which hydrochloric acid acts to convert it into pepsin. Pepsin in return causes digestion of protein. If parietal cells become non-functional it will directly affect protein digestion.