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  4. If a completely radioactive double-stranded DNA molecule undergoes two rounds of replication in a non-radioactive medium, what will be the radioactive status of the four resulting molecules?

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Q. If a completely radioactive double-stranded DNA molecule undergoes two rounds of replication in a non-radioactive medium, what will be the radioactive status of the four resulting molecules?

NTA AbhyasNTA Abhyas 2020Molecular Basis of Inheritance

Solution:

DNA replication is semiconservative, i.e., during each replication cycle, one of the parental strands is retained and a new daughter strand is obtained. Thus, only half of the parental DNA molecule is carried to the next generation.
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