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Q. Identify the labels $A, B, C$ and $D$ in the given structure of $tRNA$ and select the correct option.
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A$\,\,$ B $\,\,$ C $\,\,$ D
(a) Anticodon loop $T\Psi C $ loop AA binding site DHU loop
(b) AA binding site $T\Psi C $ loop Anticodon loop DHU loop
(c) AA binding site DHU loop Anticodon loop $T\Psi C $ loop
(d) AA binding site DHU loop $T\Psi C $ loop Anticodon loop

Molecular Basis of Inheritance

Solution:

In $tRNA$, there is a $T\Psi C $ loop which contains pseudouridine and ribothymidine. The loop is the site for attaching to ribosomes. Another loop, $DHU$ loop contains dihydrouridine. It is binding site for aminoacyl synthetase enzyme. $tRNA$ molecules have unpaired (single stranded) $CCA- OH$ sequence at the $3'$ end. This is called amino acid binding site, because the amino acid becomes covalently attached to adenylic acid or $A$ of $CCA$ sequence during polypeptide synthesis. Anticodon loop is made up of three nitrogen bases for recognising and attaching to the codon of $mRNA$.