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Q. Hyperosmotic urine secretion depends upon the

Jharkhand CECEJharkhand CECE 2015

Solution:

The ability of concentrate urine is the maximum amount of solute that can be excreted within a volumne of urine. Concentration of solutes in urine depends on the length of loop of Henie, i.e. the longer the more concentrated is urine. Fluid entering the descending limb of the loop of Henie is hypoosmptic due to the movement of solutes out of the proximal tubule. Because water, but not $ \text{N}{{\text{a}}^{\text{+}}} $ is reabsbrbed in the descending limb, the fluid in the loop of Henie becomes hyperpsmotic. As the filtrate moves through the ascending limb, $ \text{N}{{\text{a}}^{\text{+}}} $ and $ \text{C}{{\text{l}}^{-}} $ (but not water) move out of the lumen, so that the filtrate again becomes hypoosmotic and the surrounding interstitial fluid becomes hyperosmotic.