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Q. How many bands are seen when immunoglobulin $G$ molecules are analysed on a Sodium Dodecyl Sulphate-Polyacrylamide Gel Electrophoresis (SDS-PAGE) under reducing conditions?

KVPYKVPY 2015

Solution:

On SDS-PAGE of IgG, two (2) principal bands are visible. IgG antibodies is a monomeric structure consisting of heavy chains and two identical light chains. Thus, on SDS-PAGE under reducing conditions shows two bands.