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  4. Gram negative bacteria are more resistant due to the presence of in their cell wall

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Q. Gram negative bacteria are more resistant due to the presence of____ in their cell wall

UP CPMTUP CPMT 2012

Solution:

Cell wall of Gram $-ve$ bacteria is thin $(10-15\, nm)$ and hard and is not destroyed by penicillin, whereas cell wall of Gram $+ve$ bacteria is thick $(25-30 \,nm)$ and is destroyed by penicillin. Cell wall of Gram $-ve$ bacteria is less homogenous, more complex and multilayered. Lipids (including phospholipids, lipopolysaccharides and lipoproteins) make up $80-85\%$ of the total cell wall. Teichoic acids are absent in Gram $-ve$ bacteria. Presence of lipopolysaccharides in cell wall of Gram$-ve$ bacteria makes them more resistant and pathogenic.