Question

Enzymes found attached to inner membrane of mitochondria instead of matrix is/are

• A. succinic dehydrogenase
• B. cytochrome oxidase
• C. both [a] and [b]
• D. malic dehydrogenase

Answer 1

Answer: (C)

All the enzymes of Krebs cycle, fatty acid synthesis and amino acid synthesis are found in matrix but succinic dehydrogenase and cytochrome oxidase are present on inner membrane of mitochondria. The mitochondrial inner membrane contains enzymes of electron transport pathway ie, NAD, FAD, diphospho pyredine nucleotide dehydrogenase, ubiquenone or coenzyone ${{\text{Q}}_{10}},$ copper and iron; ATP synthase, succinate dehydrogenase $\text{ }\!\!\beta\!\!\text{ }-$ hydroxybutyrate dehydrogenase etc. Mitochondrial matrix contains malate dehydrogenase-isocitrate dehydrogenase, fumarase, aconitase, citrate synthase, $\text{ }\!\!\alpha\!\!\text{ }-$ keto acid dehydrogenase, $\text{ }\!\!\beta\!\!\text{ }-$ oxidation enzymes, etc.