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Q.
During which stage in the complete oxidation of glucose, are the greatest number of ATP molecules formed from ADP?
Uttarkhand PMTUttarkhand PMT 2010
Solution:
In glycolysis, four ATP and two $NADH _{2}$ molecules are formed. These two $NADH _{2}$ molecules go to electron transport chain. In oxidative decarboxylation, no ATP molecule is formed but two molecules of $NADH _{2}$ are formed from two molecules of pyruvate. These two $NADH _{2}$ go to electron transport chain. In Krebs cycle, two ATP, six $NADH _{2}$ and two molecules are formed from two molecules of acetyl Co-A. These $NADH _{2}$ and $FADH _{2}$ go to electron transport chain. In electron transport chain, all $NADH _{2}$ and $FADH _{2}$ pass to electron carriers and yield three ATP and two ATP molecules per $NADH _{2}$ and $FADH _{2}$ respectively. Thus, $4$ ATP are formed in glycolysis $2$ ATP in Krebs cycle and $34$ ATP from electron transport chain $40$ ATP Two ATP molecules are used during glycolysis. So, net gain of ATP molecules during one complete oxidation of a glucose molecule is $38$ ATP.