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  4. During an allergic reaction, the binding of antigens to IgE antibodies initiates a response, in which chemicals cause the dilation of blood vessels and a host of other physiological changes. Such chemicals are

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Q. During an allergic reaction, the binding of antigens to $IgE$ antibodies initiates a response, in which chemicals cause the dilation of blood vessels and a host of other physiological changes. Such chemicals are

AIIMSAIIMS 2009

Solution:

Histamine is released during allergic reactions. Histamine can occur in various tissues but is concentrated in connective tissue, it is formed from the amino acid histidine. It causes dilation and increases permeability of small blood vessels, which results in such symptoms as localises swelling, itching, sneezing and runny eyes and nose.