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  4. Drosophila flies with XXY genotype are females, but human beings with such genotype are abnormal males, it shows that

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Q. Drosophila flies with $XXY$ genotype are females, but human beings with such genotype are abnormal males, it shows that

AIIMSAIIMS 2007

Solution:

In human beings, the presence of a Y-chromosome is required for the development of a male sex phenotype. $X$-chromosomes present in any number $(XXX, XXXX)$ in the absence of $Y$-chromosome gives rise to female. Presence of even a single $Y$-chromosome confers maleness. In Drosophila, $Y$-chromosome plays no significant role in sex determination. In Drosophila, male determiners, were located on autosomes. One $X$ and two autosomes produce male while two $X(X, X)$ and two autosomes produce female.