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  4. Down's syndrome is caused due to of chromosomes.

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Q. Down's syndrome is caused due to ________ of chromosomes.

NTA AbhyasNTA Abhyas 2020Principles of Inheritance and Variation

Solution:

Chromosomal disorder occurs when there is addition or deletion of chromosome in the individual. In case of trisomy of the $21^{s t}$ chromosome causes Down's syndrome. This results in mental retardation and physical development is retarded as well. The palm of the individual is broad with characteristic palm crease.