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Q.
DNA content is doubled during
Odisha JEEOdisha JEE 2010Cell Cycle and Cell Division
Solution:
Inter phase is intermitotic stage of cell division in which a series of changes occur in the newly synthesized cell and the nucleus undergoes certain changes to be fit for division. Interphase is a period of intense synthesis and growth. During interphase, duplication of the chromosomes occurs. Each chromosome (called the monad) becomes double, and is then called the dyad. (resting stage). The second check point is present at the end of G2 phase, triggering the start of M phase (mitosis). Cell cycle is arrested at this phase if it detects any DNA damage. The third checkpoint occurs at metaphase (spindle checkpoint). The mitotic spindle check point takes place at the point in metaphase where all the chromosomes should have aligned at the mitotic plate and be under bipolar tension. This is sensed and initiates anaphase entry. The sensing allows degradation of cyclin B, which ensures that it no longer inhibits the anaphase promoting complex, and thus cycle continues. Thus, cell division cannot be stopped in S phase of the cellcycle.