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  4. Clover leaf model of tRNA was suggested by

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Q. Clover leaf model of tRNA was suggested by

J & K CETJ & K CET 2010Molecular Basis of Inheritance

Solution:

The existence of tRNA was first hypothesised by Francis Crick, based on the assumption that there must exist an adapter molecule capable of mediating the translation of the RNA alphabet into the protein alphabet. In 1965, a publication by Robert W Holley reported the primary structure and suggested three secondary structures. The clover leaf structure was ascertained by several other studies in the following years and was finally confirmed using X-ray crystallography studies in 1974. Two independent groups, Kim Sung Hou working under Alexander Rich and a British group headed by Aaron Klug, published the same crystallography findings within a year.